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Ohio Highway Patrol troopers seized nearly 53 pounds of cocaine in a traffic stop on Monday afternoon.
A tractor-trailer with California tags was stopped for a turn-signal violation on Interstate 70 eastbound in eastern Madison County.
Troopers say cocaine was discovered in a false wall in the front of a trailer.
Two men are facing federal felony drug charges of conspiracy to possess with intent to distribute cocaine.
The driver, Abraham A. Martinez, 48, of Monrovia, Calif., and passenger, Alfredo Ramos, 49, of Marshalltown, Iowa, are being held in the Franklin County Jail.
If convicted, the men could face life in prison.
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