The Ohio State Highway Patrol was investigating a collision between a car and a train on Monday night.
A dispatcher from the Patrol's Marion post confirmed the crash occurred on Park Avenue just east of Railroad Street in Prospect at about 7:15 p.m.
A witness indicated the car ran into the side of a CSX train engine.
"The train was blowing his horn through the crossing. And the engine's already gotten through the crossing before the impact, and it just made a big, loud bang," Mike Hempy said.
Two Prospect men in the car were seriously injured.
A medical helicopter flew Connor Helman, 18, and Brandon Phillips, 21, to Grant Medical Center in Columbus. Both men were awake and responsive, according to a friend of one of their families.
Another witness said the train crossing has needed lights to signal the approach of a train. Christi Houseworth said she wasn't sure if it would have prevented this crash.
"It scares me because cars do not slow down for the tracks at all. I knew it was going to happen sooner or later, but I've been here 45 years and this is the first car/train wreck I've seen," Christi Houseworth said.
State troopers said it appeared the conductor of the train was following procedures. Authorities were still trying to determine if alcohol or the speed of the car played any role in the crash.
The collision remained under investigation.
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