The Ohio Department of Transportation still had more than 100 plows on the roads as of noon Thursday in Delaware, Fayette, Franklin, Madison, Marion, Morrow, Pickaway and Union counties.
ODOT officials said that while interstates were clear and wet, motorists should remain attentive and cautious.
ODOT plow drivers continued to push back snow from shoulders and ramps.
Strong winds and snow whipped across many areas causing crashes and closures on Wednesday during the winter storm.
Conditions eased over much of the area Wednesday night into Thursday.
On more rural two and four lane roads throughout central Ohio, ODOT was still applying salt to hard-packed snowy patches.
In Columbus, most of the main roads had been cleared of snow by noon on Thursday.
Columbus snow crews had started working on side streets.
10TV crews did see several vehicles slide through stop signs at various intersections.
Winter weather likely contributed to at least one fatality in Ohio, when an 18-year-old woman lost control of her car and crashed into an oncoming snow plow on a highway northeast of Cincinnati.
The Hamilton County Sheriff's Office said Jessica Galley of Mason was killed at around 3 p.m. Wednesday when she lost control of her car on southbound Interstate 71, drove across the median and crashed into a northbound Ohio Department of Transportation plow.
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