City officials say several developers have expressed interest in replacing a church and several homes with a hotel or restaurant, 10TV's Jason Frazer reported.
The city says there are no concrete plans at this point.
"The city has no formal application that have been submitted seeking approval for development," said Upper Arlington Deputy City Manager Matthew Shad.
However, some residents are already voicing opposition to the idea. That includes Dan Gusty, who believes that a hotel would create safety concerns.
"People don't move to Upper Arlington for an urban environment," he said. "They move here for a nice, safe suburban community."
Others were concerned about an increase in traffic and noise.
"What hours of the night are people going to be up and down our driveway?" asked Shauna Gusty. "It could be a noise factor."
The city said that it would go to the public for input if plans developed further.
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